40-something man with SOL in pancreatic tail.

解答は以下   問題を見ていない先生はこちらをクリック

文献

・Kawamoto S Johnson PT, Hall H, Cameron JL, Hruban RH, Fishman EK

Intrapancreatic accessory spleen: CT appearance and differential diagnosis.

Abdom Imaging. 2012 Oct;37(5):812-27.

膵内副脾のCTの総説論文ですが、MRI、シンチグラフィのことも掲載されています。

よくまとまっていておすすめ

 

・Belkhir SM, Archambaud F, Prigent A, Chaumet-Riffaud P.

Intrapancreatic accessory spleen diagnosed on radionuclide imaging.

Clin Nucl Med. 2009 Sep;34(9):642-4. doi: 10.1097/RLU.0b013e3181b06b42.

 

・ Kim SH, Lee JM, Han JK, Lee JY, Kang WJ, Jang JY, Shin KS, Cho KC, Choi BI.

MDCT and superparamagnetic iron oxide (SPIO)-enhanced MR findings of intrapancreatic accessory spleen in seven patients.

Eur Radiol. 2006 Sep;16(9):1887-97. Epub 2006 Mar 18.

 

・Herédia V, Altun E, Bilaj F, Ramalho M, Hyslop BW, Semelka RC.

Gadolinium- and superparamagnetic-iron-oxide-enhanced MR findings of intrapancreatic accessory spleen in five patients.

Magn Reson Imaging. 2008 Nov;26(9):1273-8.

 

・ Jang KM, Kim SH, Lee SJ, Park MJ, Lee MH, Choi D.

Differentiation of an intrapancreatic accessory spleen from a small (<3-cm) solid pancreatic tumor: value of diffusion-weighted MR imaging.

Radiology. 2013 Jan;266(1):159-67.

IPAS の拡散強調像による診断について書かれた信頼できる論文

 

・ Kang BK, Kim JH, Byun JH, Lee SS, Kim HJ, Kim SY, Lee MG.

Diffusion-weighted MRI: usefulness for differentiating intrapancreatic accessory spleen and small hypervascular neuroendocrine tumor of the pancreas.

Acta Radiol. 2014 Dec;55(10):1157-65.

IPASの拡散強調について書かれた良い論文です。なぜかActa Radiol ですが、IPAS vs. PNETで ADCのカットオフ値も掲載されています。

 

・Motosugi  U,  Yamaguchi H, Ichikawa T, et al.

Epidermoid cyst in intrapancreatic accessory spleen: radiological findings including superparamagnetic iron oxide-enhanced magnetic resonance imaging.

J Comput Assist Tomogr. 2010 Mar-Apr;34(2):217-22. doi: 10.1097/RCT.0b013e3181c1b2bd.

山梨大学の本杉先生の自験例と過去の論文とを合わせて検討した膵内副脾由来のEpidermoid cyst の検討論文 現時点でのEpidermoid 多数例での検討の論文

74-year-old man with tumor in pancreatic tail on screening US. Answer

74才男性
超音波スクリーニングにて
膵尾部腫瘍を指摘

74-year-old man with tumor in pancreatic tail on screening US.

解答編

問題を見ていない先生はこちら

iPad version

 

 

WMV version

Key words: Pancreatic metastases, 膵転移、Renal cell carcinoma, RCC, 腎細胞癌、腎癌、腎癌膵転移、RCC, diffusion, ADC map

Key images:

Plain CT1Dynamic CT early 1Dynamic CT delay 1MRCP1T2WI 1T2WI coronal 1T1WI FS1MRI dynamic early 1MRI dynamic portal 1DWI ADCADC mapPET CT1

Referrences:

Clinical features, Prognosis

1. Song SW, Cheng JF, Liu N, Zhao TH.

Diagnosis and treatment of pancreatic metastases in 22 patients: a retrospective study.WorldJ SurgOncol. 2014 Sep 25;12:299.

2. SellnerF, Tykalsky N, De Santis M, et al.

Solitary and multiple isolated metastases of clear cell renal carcinoma to thepancreas: an indication for pancreatic surgery.

Ann SurgOncol. 2006 Jan;13(1):75-85. Epub 2006 Jan 1.

3. ZerbiA, Ortolano E, Balzano G, et al.

Pancreatic metastasis from renal cell carcinoma: which patients benefit from surgical resection?Ann SurgOncol. 2008 Apr;15(4):1161-8.

4. Law CH, Wei AC, Hanna SS,  et al.

Pancreatic resection for metastatic renal cell carcinoma: presentation, treatment, and outcome. Ann Surg Oncol.2003 Oct;10(8):922-6.

5. Sohn TA, Yeo CJ, Cameron JL, et al.

Renal cell carcinoma metastatic to the pancreas: results of surgical management.J GastrointestSurg.2001 Jul-Aug;5(4):346-51.

6. Faure JP, Tuech JJ, Richer JP, et al.

Pancreatic metastasis of renal cell carcinoma: presentation, treatment and survival. J Urol. 2001 Jan;165(1):20-2.

7. AkatsuT, Shimazu M, Aiura K, et al.

Clinicopathological features and surgical outcome of isolated metastasis of renal cell carcinoma. Hepatogastroenterology. 2007 Sep;54(78):1836-40.

Imaging features

1. Ng CS, Loyer EM, Iyer RB, David CL, DuBrow RA, Charnsangavej C.

Metastases to the pancreas from renal cell carcinoma: findings on three-phase contrast-enhanced helical CT. AJRAm J Roentgenol. 1999 Jun;172(6):1555-9.

2. Klein KA, Stephens DH, Welch TJ.

CT characteristics of metastatic disease of the pancreas. Radiographics. 1998 Mar-Apr;18(2):369-78.

3. VincenziM, Pasquotti G, Polverosi R, et al.
Imaging of pancreatic metastases from renal cell carcinoma. Cancer Imaging. 2014 Apr 22;14:5.

4. PalmowskiM, Hacke N, Satzl S, et al.

Metastasis to the pancreas: characterization by morphology and contrast enhancement features on CT and MRI. Pancreatology. 2008;8(2):199-203.

5. AscentiG, Visalli C,  Genitori A, et al.

Multiple hypervascular pancreatic metastases from renal cell carcinoma: dynamic MR and spiral CT in three cases. Clin Imaging. 2004 Sep-Oct;28(5):349-52.

6. Tsitouridis I, Diamantopoulou A, Michaelides M, et al.

Pancreatic metastases: CT and MRI findings. DiagnIntervRadiol. 2010 Mar;16(1):45-51.

RCC and ADC value

1. Choi YA, Kim CK, Park SY, et al.

Subtype differentiation of renal cell carcinoma using diffusion-weighted and blood oxygenation level-dependent MRI.AJR Am J Roentgenol. 2014 Jul;203(1):W78-84.

2. SasamoriH, Saiki M, Suyama J, et al.

Utility of apparent diffusion coefficients in the evaluation of solid renal tumors at 3T. MagnReson Med Sci. 2014;13(2):89-95.

3. Sevcenco S, Heinz-Peer G, Ponhold L, et al.

Utility and limitations of 3-Tesla diffusion-weighted magnetic resonance imaging for differentiation of renal tumors. EurJ Radiol. 2014 Jun;83(6):909-13.

4. Yu X, Lin M, Ouyang H, et al.

Application of ADC measurement in characterization of renal cell carcinomas with different pathological types and grades by 3.0T diffusion-weighted MRI.

EurJ Radiol. 2012 Nov;81(11):3061-6.

5. PaudyalB, Paudyal P, Tsushima Y, et al.

The role of the ADC value in the characterisation of renal carcinoma by diffusion-weighted MRI. Br J Radiol. 2010 Apr;83(988):336-43.

RCC and PET-CT

1. Win AZ, Aparici CM.

Clinical effectiveness of (18)f-fluorodeoxyglucose positron emission tomography/computed tomography in management of renal cell carcinoma: a single institution experience. World J Nucl Med. 2015 Jan-Apr;14(1):36-40.

2. Sharma P, Karunanithi S, Chakraborty PS, et al.

18F-Fluoride PET/CT for detection of bone metastasis in patients with renal cell carcinoma: a pilot study. NuclMed Commun. 2014 Dec;35(12):1247-53.

3. Lee H, Hwang KH, Kim SG, et al.

Can Initial (18)F-FDG PET-CT Imaging Give Information on Metastasis in Patients with Primary Renal Cell Carcinoma? NuclMed Mol Imaging. 2014 Jun;48(2):144-52.

4. Fuccio C, Ceci F, Castellucci P, et al.

Restaging clear cell renal carcinoma with 18F-FDG PET/CT. ClinNucl Med. 2014 Jun;39(6):e320-4.

5. Chen JL, Appelbaum DE, Kocherginsky M, et al.

FDG-PET as a predictive biomarker for therapy with everolimus in metastatic renal cell cancer. Cancer Med. 2013 Aug;2(4):545-52.

6. Nakhoda Z, Torigian DA, Saboury B, et al.

Assessment of the diagnostic performance of (18)F-FDG-PET/CT for detection and characterization of solid renal malignancies. Hell J Nucl Med. 2013 Jan-Apr;16(1):19-24.

7. Wang HY, Ding HJ, Chen JH, et al.

Meta-analysis of the diagnostic performance of [18F]FDG-PETand PET/CT in renal cell carcinoma. Cancer Imaging. 2012 Oct 26;12:464-74.

8. Namura K, Minamimoto R, Yao M, et al.

Impact of maximum standardized uptake value (SUVmax) evaluated by 18-Fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (18F-FDG-PET/CT) on survival for patients with advanced renal cell carcinoma: a preliminary report. BMC Cancer. 2010 Dec 3;10:667.

9. Mueller-Lisse UG, Mueller-Lisse UL.

Imaging of advanced renal cell carcinoma. World J Urol. 2010 Jun;28(3):253-61.

10. Rodríguez Martínez de Llano S, Jiménez-Vicioso A, et al.

Clinical impact of (18)F-FDG PET in management of patients with renal cell carcinoma.

Rev Esp Med Nucl. 2010 Jan-Feb;29(1):12-9.

11. Staging of renal cell carcinoma.

Mueller-Lisse UG, Mueller-Lisse UL, Meindl T, et al. EurRadiol. 2007 Sep;17(9):2268-77.

12. Ak I, Can C.

F-18 FDG PET in detecting renal cell carcinoma. ActaRadiol. 2005 Dec;46(8):895-9.

 

Pancreas症例7 回答 2014/1/27

回答ビデオ

 

iphone version

 

回答音声


Keywords:pancreas, neoplasm, solid-pseudopapillary neoplasm, SPN, very uncommon pancreatic neoplasm that predominatly affect young women,
若年女性、厚い線維性被膜、低悪性度、卵殻状石灰化、T1WI 不均一高信号、出血

keyimage
単純写真キー US3 US2 US1 GI キー33歳女性 腹痛 MRI T1, T1FS, T2WIFS 33歳女性 腹痛 MRI Dynamic 33歳女性 腹痛 CT

Pancreas 症例5 回答に文献、CT, MRI静止画像を追加 2012/3/11

key words: 漿液性嚢胞腺腫、漿液性嚢胞腺癌、膵囊胞性病変

Serous cystadenoma, SCA,  SCAs,  cystic lesions of the pancreas

 

漿液性嚢胞腺腫の文献とURL表示


・SCA の病理と対比したMDCTの診断

Shah AA, Sainani NI, Kambadakone AR, et al.

Predictive value of multi-detector computed tomography for accurate diagnosis of serous cystadenoma: radiologic-pathologic correlation.

World J Gastroenterol. 2009 Jun 14;15(22):2739-47.
http://www.ncbi.nlm.nih.gov/pubmed?term=Predictive%20value%20of%20MDCT%20for%20accurate%20diagnosis%20of%20serous
直接PDF(Free)
http://www.wjgnet.com/1007-9327/pdf/v15/i22/2739.pdf

・典型、非典型の漿液性嚢胞腺腫
Choi JY, Kim MJ, Lee JY, et al.

Typical and atypical manifestations of serous cystadenoma of the pancreas: imaging findings with pathologic correlation.

AJR Am J Roentgenol. 2009 Jul;193(1):136-42.
http://www.ncbi.nlm.nih.gov/pubmed/19542405
Free

・漿液性嚢胞腺腫:serous oligocystic adenma とMCTやIPMNとの鑑別の論文
Kim SY, Lee JM, Kim SH, Shin KS, Kim YJ, An SK, Han CJ, Han JK, Choi BI.

Macrocystic neoplasms of the pancreas: CT differentiation of serous oligocystic adenoma from mucinous cystadenoma and intraductal papillary mucinous tumor.

AJR Am J Roentgenol. 2006 Nov;187(5):1192-8.

http://www.ncbi.nlm.nih.gov/pubmed/17056905

Free


・膵嚢胞性病変のまとめ論文

Kalb B, Sarmiento JM, Kooby DA, et al.
MR imaging of cystic lesions of the pancreas.
Radiographics. 2009 Oct;29(6):1749-65.

http://www.ncbi.nlm.nih.gov/pubmed/19959519

2012年3月3日現在Free


・膵充実と囊胞性病変の拡散強調像論文まとめ

Wang Y, Miller FH, Chen ZE, et al.
Diffusion-weighted MR imaging of solid and cystic lesions of the pancreas.
Radiographics. 2011 May-Jun;31(3):E47-64. Review.

http://www.ncbi.nlm.nih.gov/pubmed/21721197

Not Free


・SCN の臨床的特徴の論文

Fukasawa M, Maguchi H, Takahashi K, et al.
Clinical features and natural history of serous cystic neoplasm of the pancreas.
Pancreatology. 2010;10(6):695-701. Epub 2011 Jan 18.

http://www.ncbi.nlm.nih.gov/pubmed/21242709

Free


・PK と SCN, MCT, 偽嚢胞との鑑別

Lv P, Mahyoub R, Lin X, et al.
Differentiating pancreatic ductal adenocarcinoma from pancreatic serous cystadenoma, mucinous cystadenoma, and a pseudocyst with detailed analysis of cystic features on CT scans: a preliminary study.
Korean J Radiol. 2011 Mar-Apr;12(2):187-95. Epub 2011 Mar 3.
http://www.ncbi.nlm.nih.gov/pubmed/21430935
Free

・大腸と脾臓に浸潤した悪性SCCs の症例
Cho W, Cho YB, Jang KT, et al.
Pancreatic serous cystadenocarcinoma with invasive growth into the colon and spleen.
J Korean Surg Soc. 2011 Sep;81(3):221-4. Epub 2011 Sep 26.
http://thesurgery.or.kr/DOIx.php?id=10.4174/jkss.2011.81.3.221
Free

Bano S, Upreti L, Puri SK, Chaudhary V, Sakuja P.
Imaging of pancreatic serous cystadenocarcinoma.
Jpn J Radiol. 2011 Dec;29(10):730-4. Epub 2011 Oct 19.
http://www.ncbi.nlm.nih.gov/pubmed?term=Bano%20S%2C%20Upreti%20L%2C%20Puri%20SK%2C%20Chaudhary%20V%2C%20Sakuja%20P.%20Imaging%20of%20pancreatic%20serous%20cystadenocarcinoma.

Lahat G, Lubezky N, Haim MB, et al.
Cystic tumors of the pancreas: high malignant potential.
Isr Med Assoc J 2011 May;13(5):284-9.
http://www.ima.org.il/imaj/dynamic/web/ArtFromPubmed.asp?year=2011&month=05&page=284

King JC, Ng TT, White SC, Cortina G, Reber HA, Hines OJ.
Pancreatic serous cystadenocarcinoma: a case report and review of the literature.
J Gastrointest Surg. 2009 Oct;13(10):1864-8. Epub 2009 May 21. Review.
http://www.ncbi.nlm.nih.gov/pubmed/19459016

・腫瘍の大きさと部位と臨床所見との関連性
Khashab MA, Shin EJ, Amateau S, et al.

Tumor size and location correlate with behavior of pancreatic serous cystic neoplasms.

Am J Gastroenterol. 2011 Aug;106(8):1521-6. doi: 10.1038/ajg.2011.117. Epub 2011 Apr 5.

http://www.nature.com/ajg/journal/v106/n8/full/ajg2011117a.html

キー画像

膵頭部から鈎部に分葉状の低吸収域腫瘤を認める

膵実質相では強く濃染する充実様に見える部分と囊胞性部分が混在

充実部分にみえ、よく濃染していた部位はwash out されている

 

DWI では高信号信号を示す

腫瘤はかなり強い高信号を示す。ADC値=2.84×10-3mm2/s

MRCP 2D multislce 多数の小嚢胞から構成される

MRCP: Single thick slub  多数の小嚢胞で構成されているT2WI axial  蜂巣状の囊胞性病変