エキスパートはこう考える第11回 回答

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key words: 急性肺障害、薬剤性肺障害、成人呼吸窮迫症候群、ARDS, 牽引性気管支拡張、容量減少、volume loss、広範囲スリガラス陰影、グリフォサート、ラウンドアップ、除草剤

文献:ラウンドアップによる肺障害 Pushnoy LA, Avnon LS, Carel RS. Herbicide (Roundup) pneumonitis Chest. 1998 Dec;114(6):1769-71. http://chestjournal.chestpubs.org/content/114/6/1769.long

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初回胸部単純写真

第3病日胸部単純写真

第3病日胸部単純写真右下肺野拡大

第4病日単純写真

第4病日単純写真 focus

第12病日胸部単純

第12病日胸部単純右下肺野拡大

2 回目CT と同日の胸部単純写真

第20病日の胸部CT1

第20病日の胸部CT2

第26病日の胸部CT1

第26病日の胸部CT1

エキスパートはこう考える第10回 回答

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<key words>chronic eosinophilic pneumonia, reversed halo sign、Loeffler’s syndrome, 慢性好酸球性肺炎、レフレル症候群、BOOP,COP

<参考文献>

Chronic eosinophilic pneumonia
Jeong YJ, Kim KI, Seo IJ, Lee CH, Lee KN, Kim KN, Kim JS, Kwon WJ.
Eosinophilic lung diseases: a clinical, radiologic, and pathologic overview.
Radiographics. 2007 May-Jun;27(3):617-37; discussion 637-9. Review.
http://radiographics.rsna.org/content/27/3/617.full.pdf+html

Kim SJ, Lee KS, Ryu YH, Yoon YC, Choe KO, Kim TS, Sung KJ.
Reversed halo sign on high-resolution CT of cryptogenic organizing pneumonia: diagnostic implications.
AJR Am J Roentgenol. 2003 May;180(5):1251-4.
http://www.ajronline.org/cgi/reprint/180/5/1251

Arakawa H, Kurihara Y, Niimi H, Nakajima Y, Johkoh T, Nakamura H.
Bronchiolitis obliterans with organizing pneumonia versus chronic eosinophilic pneumonia: high-resolution CT findings in 81 patients.
AJR Am J Roentgenol. 2001 Apr;176(4):1053-8.
http://www.ajronline.org/cgi/reprint/176/4/1053

Johkoh T, Muller NL, Akira M, et al.
Eosinophilic lung diseases: diagnostic accuracy of thin-section CT in 111 patients.
Radiology. 2000 Sep;216(3):773-80
http://radiology.rsna.org/content/216/3/773.full.pdf+html

Kim Y, Lee KS, Choi DC, Primack SL, Im JG.
The spectrum of eosinophilic lung disease: radiologic findings.
J Comput Assist Tomogr. 1997 Nov-Dec;21(6):920-30.

Ebara H, Ikezoe J, Johkoh T, Kohno N, Takeuchi N, Kozuka T, Ishida O.
Chronic eosinophilic pneumonia: evolution of chest radiograms and CT features.
J Comput Assist Tomogr. 1994 Sep-Oct;18(5):737-44.

Yoshida K, Shijubo N, Koba H, Mori Y, Satoh M, Morikawa T, Abe S.
Chronic eosinophilic pneumonia progressing to lung fibrosis.
Eur Respir J. 1994 Aug;7(8):1541-4.
http://erj.ersjournals.com/content/7/8/1541.long

Hayakawa H, Sato A, Toyoshima M, Imokawa S, Taniguchi M
A clinical study of idiopathic eosinophilic pneumonia.
Chest. 1994 May;105(5):1462-6.

Mayo JR, Muller NL, Road J, Sisler J, Lillington G.
Chronic eosinophilic pneumonia: CT findings in six cases.
AJR Am J Roentgenol. 1989 Oct;153(4):727-30.
http://www.ajronline.org/cgi/reprint/153/4/727

Reversed halo sign
Tzilas V, Bastas A, Provata A, Koti A, Tzouda V, Tsoukalas G.
The “reversed halo” sign in pneumonococcal pneumonia: a review with a case report.
Eur Rev Med Pharmacol Sci. 2010 May;14(5):481-6. Review.

Marchiori E, Zanetti G, Hochhegger B, Carvalho JF.
Sarcoid cluster sign and the reversed halo sign: Extending the spectrum of radiographic manifestations in sarcoidosis.
Eur J Radiol. 2010 May 18. [Epub ahead of print] No abstract available.

Marchiori E, Grando RD, Simoes Dos Santos CE, Maffazzioli Santos Balzan L, Zanetti G, Mano CM, Gutierrez RS.
Pulmonary tuberculosis associated with the reversed halo sign on high-resolution CT.
Br J Radiol. 2010 Mar;83(987):e58-60.

Benamore RE, Weisbrod GL, Hwang DM, Bailey DJ, Pierre AF, Lazar NM, Maimon N.
Reversed halo sign in lymphomatoid granulomatosis.
Br J Radiol. 2007 Aug;80(956):e162-6.
http://bjr.birjournals.org/cgi/reprint/80/956/e162

Arai T, Inoue Y, Ando S, Inoue K, Tsuyuguchi K, Suzuki K, Hayashi S, Kitaichi M, Akira M, Sakatani M.
[A case of cryptogenic organizing pneumonia showing reversed halo sign on computed tomography of the chest]
Nihon Kokyuki Gakkai Zasshi. 2007 Aug;45(8):621-6. Japanese.

Ueda S, Inoue R, Tanaka K, Mizumori Y, Kawamura T, Nakahara Y, Mochizuki Y, Kobashi Y.
[A case of nonspecific interstitial pneumonia with reversed halo sign on chest HRCT]
Nihon Kokyuki Gakkai Zasshi. 2007 Mar;45(3):248-52. Japanese.

Gasparetto EL, Escuissato DL, Davaus T, de Cerqueira EM, Souza AS Jr, Marchiori E, Muller NL.
Reversed halo sign in pulmonary paracoccidioidomycosis.
AJR Am J Roentgenol. 2005 Jun;184(6):1932-4.
http://www.ajronline.org/cgi/reprint/184/6/1932

Kim SJ, Lee KS, Ryu YH, Yoon YC, Choe KO, Kim TS, Sung KJ.
Reversed halo sign on high-resolution CT of cryptogenic organizing pneumonia: diagnostic implications.
AJR Am J Roentgenol. 2003 May;180(5):1251-4.
http://www.ajronline.org/cgi/reprint/180/5/1251

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エキスパートはこう考える第9回 回答

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<Key words>マイコプラズマ肺炎、気管支肺炎、コンソリデーション,マクロライド系抗生物質、mycoplasma pneumoniae pneumonia, bronchopneumonia, consolidation

<参考文献>

Miyashita N, Sugiu T, Kawai Y, Oda K, Yamaguchi T, Ouchi K, Kobashi Y, Oka M.
Radiographic features of Mycoplasma pneumoniae pneumonia: differential diagnosis and performance timing.
BMC Med Imaging. 2009 Apr 29;9:7.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680832/pdf/1471-2342-9-7.pdf

Nei T, Yamano Y, Sakai F, Kudoh S.
Mycoplasma pneumoniae pneumonia: differential diagnosis by computerized tomography.
Intern Med. 2007;46(14):1083-7. Epub 2007 Jul 17.
http://www.jstage.jst.go.jp/article/internalmedicine/46/14/1083/_pdf

Nambu A, Saito A, Araki T, Ozawa K, Hiejima Y, Akao M, Ohki Z, Yamaguchi H.
Chlamydia pneumoniae: comparison with findings of Mycoplasma pneumoniae and Streptococcus pneumoniae at thin-section CT.
Radiology. 2006 Jan;238(1):330-8. Epub 2005 Nov 22.

http://radiology.rsna.org/content/238/1/330.long

Lee I, Kim TS, Yoon HK.
Mycoplasma pneumoniae pneumonia: CT features in 16 patients.
Eur Radiol. 2006 Mar;16(3):719-25. Epub 2005 Oct 8.

Okada F, Ando Y, Wakisaka M, Matsumoto S, Mori H.
Chlamydia pneumoniae pneumonia and Mycoplasma pneumoniae pneumonia: comparison of clinical findings and CT findings.
J Comput Assist Tomogr. 2005 Sep-Oct;29(5):626-32.

Reittner P, Ward S, Heyneman L, Johkoh T, Muller NL.
Pneumonia: high-resolution CT findings in 114 patients.
Eur Radiol. 2003 Mar;13(3):515-21. Epub 2002 Aug 3.

Reittner P, Muller NL, Heyneman L, Johkoh T, Park JS, Lee KS, Honda O, Tomiyama N.
Mycoplasma pneumoniae pneumonia: radiographic and high-resolution CT features in 28 patients.
AJR Am J Roentgenol. 2000 Jan;174(1):37-41.
http://www.ajronline.org/cgi/reprint/174/1/37

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単純写真 単純写真(拡大)
単純写真(拡大) 単純写真(2日後)
CT画像(二日後の単純写真と同日に撮影) CT画像(二日後の単純写真と同日に撮影)
CT画像(二日後の単純写真と同日に撮影) CT画像(二日後の単純写真と同日に撮影)

エキスパートはこう考える第8回 回答

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<キーワード>RA, Rheumatoid arthritis, PCP, pneumocystis pneumonia, panlobular distribution, MTX, methotrexate, リウマチ、ニューモシスチス肺炎、氾小葉性分布,メトトレキセートによる薬剤性肺障害

<参考文献>

pneumocystis pneumonia with rheumatoid arthritis
Tasaka S, Tokuda H, Sakai F, et al.
Comparison of clinical and radiological features of pneumocystis pneumonia between malignancy cases and acquired immunodeficiency syndrome cases: a multicenter study.
Intern Med. 2010;49(4):273-81. Epub 2010 Feb 15.

Tokuda H, Sakai F, Yamada H, et al.
Clinical and radiological features of Pneumocystis pneumonia in patients with rheumatoid arthritis, in comparison with methotrexate pneumonitis and Pneumocystis pneumonia in acquired immunodeficiency syndrome
Intern Med. 2008;47(10):915-23. Epub 2008 May 15.

Minagawa S, Takayanagi N, Hara K, et al.
A case of rheumatoid arthritis complicated with methotrexate-induced pneumonitis and pneumocystis pneumonia
Nihon Kokyuki Gakkai Zasshi. 2008 Mar;46(3):237-42.

Mori S, Cho I, Ichiyasu H, et al.
Asymptomatic carriage of Pneumocystis jiroveci in elderly patients with rheumatoid arthritis in Japan: a possible association between colonization and development of Pneumocystis jiroveci pneumonia during low-dose MTX therapy.
Mod Rheumatol. 2008;18(3):240-6. Epub 2008 Feb 29.

Kaneko Y, Suwa A, Ikeda Y, et al.
Pneumocystis jiroveci pneumonia associated with low-dose methotrexate treatment for rheumatoid arthritis: report of two cases and review of the literature.
Mod Rheumatol. 2006;16(1):36-8.

pneumocystis pneumonia
Bergin CJ, Wirth RL, Berry GJ, et al.
Pneumocystis carinii pneumonia: CT and HRCT observations.
J Comput Assist Tomog. 1990 Sep-Oct;14(5):756-9.

Kuhlman JE, Kavuru M, Fishman EK, et al.
Pneumocystis carinii pneumonia: spectrum of parenchymal CT findings.
Radiology. 1990 Jun;175(3):711-4.

Feurestein IM, Archer A, Pluda JM, et al.
Thin-walled cavities, cysts, and pneumothorax in Pneumocystis carinii pneumonia: further observations with histopathologic correlation.
Radiology. 1990 Mar;174(3 Pt 1):697-702.

Hidalgo A, Falco V, Mauleon S, et al.
Accuracy of high-resolution CT in distinguishing between Pneumocystis carinii pneumonia and non- Pneumocystis carinii pneumonia in AIDS patients.
Eur Radiol. 2003 May;13(5):1179-84. Epub 2002 Sep 25.

Boiselle PM, Crans CA Jr, Kaplan MA
The changing face of Pneumocystis carinii pneumonia in AIDS patients.
AJR Am J Roentgenol. 1999 May;172(5):1301-9.

Gruden JF, Huang L, Turner J, et al.
High-resolution CT in the evaluation of clinically suspected Pneumocystis carinii pneumonia in AIDS patients with normal, equivocal, or nonspecific radiographic findings.
AJR Am J Roentgenol. 1997 Oct;169(4):967-75.

Tsukada H, Yoshimura N, Yamamoto T, et al.
[High-resolution CT findings of Pneumocystis carinii pneumonia]
Nippon Igaku Hoshasen Gakkai Zassh. 1995 May;55(6):369-74.

Hartman TE, Primack SL, Muller NL, et al.
Diagnosis of thoracic complications in AIDS: accuracy of CT.
AJR Am J Roentgenol. 1994 Mar;162(3):547-53.

Moskovic E, Miller R, Pearson M.
High resolution computed tomography of Pneumocystis carinii pneumonia in AIDS.
Clin Radiol. 1990 Oct;42(4):239-43.

crazy-paving pattern
Rossi SE, Erasmus JJ, Volpacchio M, et al.
“Crazy-paving” pattern at thin-section CT of the lungs: radiologic-pathologic overview.
Radiographics. 2003 Nov-Dec;23(6):1509-19.

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