エキスパートはこう考える第8回　回答

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<キーワード＞RA, Rheumatoid arthritis, PCP, pneumocystis pneumonia, panlobular distribution, MTX, methotrexate, リウマチ、ニューモシスチス肺炎、氾小葉性分布，メトトレキセートによる薬剤性肺障害

＜参考文献＞

pneumocystis pneumonia with rheumatoid arthritis
Tasaka S, Tokuda H, Sakai F, et al.
Comparison of clinical and radiological features of pneumocystis pneumonia between malignancy cases and acquired immunodeficiency syndrome cases: a multicenter study.
Intern Med. 2010;49(4):273-81. Epub 2010 Feb 15.

Tokuda H, Sakai F, Yamada H, et al.
Clinical and radiological features of Pneumocystis pneumonia in patients with rheumatoid arthritis, in comparison with methotrexate pneumonitis and Pneumocystis pneumonia in acquired immunodeficiency syndrome
Intern Med. 2008;47(10):915-23. Epub 2008 May 15.

Minagawa S, Takayanagi N, Hara K, et al.
A case of rheumatoid arthritis complicated with methotrexate-induced pneumonitis and pneumocystis pneumonia
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Mori S, Cho I, Ichiyasu H, et al.
Asymptomatic carriage of Pneumocystis jiroveci in elderly patients with rheumatoid arthritis in Japan: a possible association between colonization and development of Pneumocystis jiroveci pneumonia during low-dose MTX therapy.
Mod Rheumatol. 2008;18(3):240-6. Epub 2008 Feb 29.

Kaneko Y, Suwa A, Ikeda Y, et al.
Pneumocystis jiroveci pneumonia associated with low-dose methotrexate treatment for rheumatoid arthritis: report of two cases and review of the literature.
Mod Rheumatol. 2006;16(1):36-8.

pneumocystis pneumonia
Bergin CJ, Wirth RL, Berry GJ, et al.
Pneumocystis carinii pneumonia: CT and HRCT observations.
J Comput Assist Tomog. 1990 Sep-Oct;14(5):756-9.

Kuhlman JE, Kavuru M, Fishman EK, et al.
Pneumocystis carinii pneumonia: spectrum of parenchymal CT findings.
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Feurestein IM, Archer A, Pluda JM, et al.
Thin-walled cavities, cysts, and pneumothorax in Pneumocystis carinii pneumonia: further observations with histopathologic correlation.
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Hidalgo A, Falco V, Mauleon S, et al.
Accuracy of high-resolution CT in distinguishing between Pneumocystis carinii pneumonia and non- Pneumocystis carinii pneumonia in AIDS patients.
Eur Radiol. 2003 May;13(5):1179-84. Epub 2002 Sep 25.

Boiselle PM, Crans CA Jr, Kaplan MA
The changing face of Pneumocystis carinii pneumonia in AIDS patients.
AJR Am J Roentgenol. 1999 May;172(5):1301-9.

Gruden JF, Huang L, Turner J, et al.
High-resolution CT in the evaluation of clinically suspected Pneumocystis carinii pneumonia in AIDS patients with normal, equivocal, or nonspecific radiographic findings.
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Tsukada H, Yoshimura N, Yamamoto T, et al.
[High-resolution CT findings of Pneumocystis carinii pneumonia]
Nippon Igaku Hoshasen Gakkai Zassh. 1995 May;55(6):369-74.

Hartman TE, Primack SL, Muller NL, et al.
Diagnosis of thoracic complications in AIDS: accuracy of CT.
AJR Am J Roentgenol. 1994 Mar;162(3):547-53.

Moskovic E, Miller R, Pearson M.
High resolution computed tomography of Pneumocystis carinii pneumonia in AIDS.
Clin Radiol. 1990 Oct;42(4):239-43.

crazy-paving pattern
Rossi SE, Erasmus JJ, Volpacchio M, et al.
“Crazy-paving” pattern at thin-section CT of the lungs: radiologic-pathologic overview.
Radiographics. 2003 Nov-Dec;23(6):1509-19.

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