エキスパートはこう考える第9回 回答

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<Key words>マイコプラズマ肺炎、気管支肺炎、コンソリデーション,マクロライド系抗生物質、mycoplasma pneumoniae pneumonia, bronchopneumonia, consolidation

<参考文献>

Miyashita N, Sugiu T, Kawai Y, Oda K, Yamaguchi T, Ouchi K, Kobashi Y, Oka M.
Radiographic features of Mycoplasma pneumoniae pneumonia: differential diagnosis and performance timing.
BMC Med Imaging. 2009 Apr 29;9:7.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680832/pdf/1471-2342-9-7.pdf

Nei T, Yamano Y, Sakai F, Kudoh S.
Mycoplasma pneumoniae pneumonia: differential diagnosis by computerized tomography.
Intern Med. 2007;46(14):1083-7. Epub 2007 Jul 17.
http://www.jstage.jst.go.jp/article/internalmedicine/46/14/1083/_pdf

Nambu A, Saito A, Araki T, Ozawa K, Hiejima Y, Akao M, Ohki Z, Yamaguchi H.
Chlamydia pneumoniae: comparison with findings of Mycoplasma pneumoniae and Streptococcus pneumoniae at thin-section CT.
Radiology. 2006 Jan;238(1):330-8. Epub 2005 Nov 22.

http://radiology.rsna.org/content/238/1/330.long

Lee I, Kim TS, Yoon HK.
Mycoplasma pneumoniae pneumonia: CT features in 16 patients.
Eur Radiol. 2006 Mar;16(3):719-25. Epub 2005 Oct 8.

Okada F, Ando Y, Wakisaka M, Matsumoto S, Mori H.
Chlamydia pneumoniae pneumonia and Mycoplasma pneumoniae pneumonia: comparison of clinical findings and CT findings.
J Comput Assist Tomogr. 2005 Sep-Oct;29(5):626-32.

Reittner P, Ward S, Heyneman L, Johkoh T, Muller NL.
Pneumonia: high-resolution CT findings in 114 patients.
Eur Radiol. 2003 Mar;13(3):515-21. Epub 2002 Aug 3.

Reittner P, Muller NL, Heyneman L, Johkoh T, Park JS, Lee KS, Honda O, Tomiyama N.
Mycoplasma pneumoniae pneumonia: radiographic and high-resolution CT features in 28 patients.
AJR Am J Roentgenol. 2000 Jan;174(1):37-41.
http://www.ajronline.org/cgi/reprint/174/1/37

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単純写真 単純写真(拡大)
単純写真(拡大) 単純写真(2日後)
CT画像(二日後の単純写真と同日に撮影) CT画像(二日後の単純写真と同日に撮影)
CT画像(二日後の単純写真と同日に撮影) CT画像(二日後の単純写真と同日に撮影)

エキスパートはこう考える第8回 回答

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<キーワード>RA, Rheumatoid arthritis, PCP, pneumocystis pneumonia, panlobular distribution, MTX, methotrexate, リウマチ、ニューモシスチス肺炎、氾小葉性分布,メトトレキセートによる薬剤性肺障害

<参考文献>

pneumocystis pneumonia with rheumatoid arthritis
Tasaka S, Tokuda H, Sakai F, et al.
Comparison of clinical and radiological features of pneumocystis pneumonia between malignancy cases and acquired immunodeficiency syndrome cases: a multicenter study.
Intern Med. 2010;49(4):273-81. Epub 2010 Feb 15.

Tokuda H, Sakai F, Yamada H, et al.
Clinical and radiological features of Pneumocystis pneumonia in patients with rheumatoid arthritis, in comparison with methotrexate pneumonitis and Pneumocystis pneumonia in acquired immunodeficiency syndrome
Intern Med. 2008;47(10):915-23. Epub 2008 May 15.

Minagawa S, Takayanagi N, Hara K, et al.
A case of rheumatoid arthritis complicated with methotrexate-induced pneumonitis and pneumocystis pneumonia
Nihon Kokyuki Gakkai Zasshi. 2008 Mar;46(3):237-42.

Mori S, Cho I, Ichiyasu H, et al.
Asymptomatic carriage of Pneumocystis jiroveci in elderly patients with rheumatoid arthritis in Japan: a possible association between colonization and development of Pneumocystis jiroveci pneumonia during low-dose MTX therapy.
Mod Rheumatol. 2008;18(3):240-6. Epub 2008 Feb 29.

Kaneko Y, Suwa A, Ikeda Y, et al.
Pneumocystis jiroveci pneumonia associated with low-dose methotrexate treatment for rheumatoid arthritis: report of two cases and review of the literature.
Mod Rheumatol. 2006;16(1):36-8.

pneumocystis pneumonia
Bergin CJ, Wirth RL, Berry GJ, et al.
Pneumocystis carinii pneumonia: CT and HRCT observations.
J Comput Assist Tomog. 1990 Sep-Oct;14(5):756-9.

Kuhlman JE, Kavuru M, Fishman EK, et al.
Pneumocystis carinii pneumonia: spectrum of parenchymal CT findings.
Radiology. 1990 Jun;175(3):711-4.

Feurestein IM, Archer A, Pluda JM, et al.
Thin-walled cavities, cysts, and pneumothorax in Pneumocystis carinii pneumonia: further observations with histopathologic correlation.
Radiology. 1990 Mar;174(3 Pt 1):697-702.

Hidalgo A, Falco V, Mauleon S, et al.
Accuracy of high-resolution CT in distinguishing between Pneumocystis carinii pneumonia and non- Pneumocystis carinii pneumonia in AIDS patients.
Eur Radiol. 2003 May;13(5):1179-84. Epub 2002 Sep 25.

Boiselle PM, Crans CA Jr, Kaplan MA
The changing face of Pneumocystis carinii pneumonia in AIDS patients.
AJR Am J Roentgenol. 1999 May;172(5):1301-9.

Gruden JF, Huang L, Turner J, et al.
High-resolution CT in the evaluation of clinically suspected Pneumocystis carinii pneumonia in AIDS patients with normal, equivocal, or nonspecific radiographic findings.
AJR Am J Roentgenol. 1997 Oct;169(4):967-75.

Tsukada H, Yoshimura N, Yamamoto T, et al.
[High-resolution CT findings of Pneumocystis carinii pneumonia]
Nippon Igaku Hoshasen Gakkai Zassh. 1995 May;55(6):369-74.

Hartman TE, Primack SL, Muller NL, et al.
Diagnosis of thoracic complications in AIDS: accuracy of CT.
AJR Am J Roentgenol. 1994 Mar;162(3):547-53.

Moskovic E, Miller R, Pearson M.
High resolution computed tomography of Pneumocystis carinii pneumonia in AIDS.
Clin Radiol. 1990 Oct;42(4):239-43.

crazy-paving pattern
Rossi SE, Erasmus JJ, Volpacchio M, et al.
“Crazy-paving” pattern at thin-section CT of the lungs: radiologic-pathologic overview.
Radiographics. 2003 Nov-Dec;23(6):1509-19.

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胸部単純写真全体像 右肩関節
左肩関節 左肩関節フォーカス
CT1 CT2
CT3 CT4

エキスパートはこう考える第7回 回答

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<Key words>ブラ壁肥厚、菌球、fungus ball、 アスペルギルス症、アスペルギローマ、aspergilloma, invasive aspergillosis, semi-invasive aspergillosis, ABPA, 宿主や局所の免疫状態

<論文>

日本語のまとまった肺真菌症のPDF
国立病院機構東京病院臨床研究部長 倉島 篤行 のPDFより引用リンク
http://medical.radionikkei.jp/abbott/final/pdf/051125.pdf

Agarwal R, Gupta D, Aggarwal AN, et al.
Clinical significance of hyperattenuating mucoid impaction in allergic bronchopulmonary aspergillosis: an analysis of 155 patients.
Chest. 2007 Oct;132(4):1183-90. Epub 2007 Jul 23.
http://chestjournal.chestpubs.org/content/132/4/1183.full.pdf+html

Jeong YJ, Kim KI, Seo IJ, et al.
Eosinophilic lung diseases: a clinical, radiologic, and pathologic overview.
Radiographics. 2007 May-Jun;27(3):617-37; discussion 637-9.

Kobashi Y, Fukuda M, Yoshida K, Miyashita N, Niki Y, Oka M.
Chronic necrotizing pulmonary aspergillosis as a complication of pulmonary Mycobacterium avium complex disease.
Respirology. 2006 Nov;11(6):809-13.

Althoff Souza C, Muller NL, Marchiori E, et al.
Pulmonary invasive aspergillosis and candidiasis in immunocompromised patients: a comparative study of the high-resolution CT findings.
J Thorac Imaging. 2006 Aug;21(3):184-9.

Agarwal R, Gupta D, Aggarwal AN, et al.
Allergic bronchopulmonary aspergillosis: lessons from 126 patients attending a chest clinic in north India.
Chest. 2006 Aug;130(2):442-8.
http://chestjournal.chestpubs.org/content/130/2/442.full.pdf+html

Brodoefel H, Vogel M, Hebart H, et al.
Long-term CT follow-up in 40 non-HIV immunocompromised patients with invasive pulmonary aspergillosis: kinetics of CT morphology and correlation with clinical findings and outcome.
AJR Am J Roentgenol. 2006 Aug;187(2):404-13.
http://www.ajronline.org/cgi/reprint/187/2/404

Horger M, Hebart H, Einsele H, et al.
Initial CT manifestations of invasive pulmonary aspergillosis in 45 non-HIV immunocompromised patients: association with patient outcome?
Eur J Radiol. 2005 Sep;55(3):437-44. Epub 2005 Jan 28

Lee YR, Choi YW, Lee KJ, et al.
CT halo sign: the spectrum of pulmonary diseases.
Br J Radiol. 2005 Sep;78(933):862-5. Review.
http://bjr.birjournals.org/cgi/reprint/78/933/862

Horger M, Einsele H, Schumacher U, Wehrmann M, Hebart H, Lengerke C, Vonthein R, Claussen CD, Pfannenberg C.
Invasive pulmonary aspergillosis: frequency and meaning of the “hypodense sign” on unenhanced CT.
Br J Radiol. 2005 Aug;78(932):697-703.
http://bjr.birjournals.org/cgi/reprint/78/932/697

Sonnet S, Buitrago-Tellez CH, Tamm M, et al.
Direct detection of angioinvasive pulmonary aspergillosis in immunosuppressed patients: preliminary results with high-resolution 16-MDCT angiography.
AJR Am J Roentgenol. 2005 Mar;184(3):746-51.
http://www.ajronline.org/cgi/reprint/184/3/746

Andreu J, Caceres J, Pallisa E, et al.
Radiological manifestations of pulmonary tuberculosis.
Eur J Radiol. 2004 Aug;51(2):139-49.

Franquet T, Gimenez A, Hidalgo A.
Imaging of opportunistic fungal infections in immunocompromised patient.
Eur J Radiol. 2004 Aug;51(2):130-8.

Buckingham SJ, Hansell DM
Aspergillus in the lung: diverse and coincident forms.
Eur Radiol. 2003 Aug;13(8):1786-800. Epub 2003 May 29.

Kang EY, Kim DH, Woo OH, et al.
Pulmonary aspergillosis in immunocompetent hosts without underlying lesions of the lung: radiologic and pathologic findings.
AJR Am J Roentgenol. 2002 Jun;178(6):1395-9.
http://www.ajronline.org/cgi/reprint/178/6/1395

Franquet T, Serrano F, Gimenez A, et al.
Necrotizing aspergillosis of large airways: CT findings in eight patients.
J Comput Assist Tomogr. 2002 May-Jun;26(3):342-5.

Kato T, Usami I, Morita H, et al.
Chronic necrotizing pulmonary aspergillosis in pneumoconiosis: clinical and radiologic findings in 10 patients.
Chest. 2002 Jan;121(1):118-27.
http://chestjournal.chestpubs.org/content/121/1/118.full.pdf+html

Soubani AO, Chandrasekar PH
The clinical spectrum of pulmonary aspergillosis.
Chest. 2002 Jun;121(6):1988-99.
http://chestjournal.chestpubs.org/content/121/6/1988.full.pdf+html

Franquet T, Muller NL, Gimenez A, et al.
Spectrum of pulmonary aspergillosis: histologic, clinical, and radiologic findings.
Radiographics. 2001 Jul-Aug;21(4):825-37. Review.
http://radiographics.rsna.org/content/21/4/825.full.pdf+html

Kim MJ, Lee KS, Kim J, et al.
Crescent sign in invasive pulmonary aspergillosis: frequency and related CT and clinical factors.
J Comput Assist Tomogr. 2001 Mar-Apr;25(2):305-10.

Aquino SL, Kee ST, Warnock ML, et al.
Pulmonary aspergillosis: imaging findings with pathologic correlation.
AJR Am J Roentgenol. 1994 Oct;163(4):811-5.
http://www.ajronline.org/cgi/reprint/163/4/811

Greene R
The pulmonary aspergilloses: three distinct entities or a spectrum of disease.
Radiology 1981 Aug;140(2):527-30.

Klein DL, Gamus G
Thoracic manifestations of aspergillosis.
AJR Am J Roentgneol. 1980 Mar;134(3):543-52.
http://www.ajronline.org/cgi/reprint/134/3/543
単純写真のみをまとめたレビュー論文

内科系論文
Bulpa P, Dive A, Sibille Y.
Invasive pulmonary aspergillosis in patients with chronic obstructive pulmonary disease.
Eur Respir J. 2007 Oct;30(4):782-800.
http://erj.ersjournals.com/cgi/reprint/30/4/782

Muquim A, Dial S, Menzies D.
Invasive aspergillosis in patients with chronic obstructive pulmonary diseases.
Can Respir J. 2005 May-Jun;12(4):199-204.
http://www.ncbi.nlm.nih.gov/sites/pubmed  右上のFull text article pulsus をクリックした後、さらに PDF/Free をクリックするとPDFが入手可能

 

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